• Cardiologs is the world’s most advanced cloud-based and Artificial Intelligence-powered ECG analysis solution to aid healthcare professionals in screening for arrhythmias such as AFib using ambulatory ECG monitoring recordings.

    PARIS, July 5, 2017—Cardiologs Technologies SAS announced today that it has received FDA clearance
    of its Cardiologs ECG Analysis Platform, a cloud-based cardiac monitoring-analysis web service powered by
    artificial intelligence (AI). Cardiologs aids physicians in screening for atrial fibrillation (AFib) and other arrhythmias
    using long-term ambulatory ECG monitoring recordings. The Cardiologs system is also CE-marked in Europe.
    Atrial fibrillation (AFib) is the most common human arrhythmia, affecting about 33 million patients worldwide. AFib
    is a growing problem in cardiovascular disease and is associated with an increased risk of severe stroke, heart
    failure, and death. AFib is often asymptomatic, with stroke as the first manifestation. Indeed, recent stroke
    registries indicate that AFib is associated with one-third of all ischemic strokes.

    “It is intuitive that screening for AFib and subsequent anticoagulant treatment should reduce the stroke burden,
    which is the basis of guideline recommendations to screen for AFib in persons over the age of 65,” said Dr.
    Arnaud Rosier, cardiac electrophysiologist at the Hôpital Jacques Cartier, Massy. “Unfortunately, current R-R
    interval based methods to detect AFib are characterized by an inferior Positive Predictive Value (PPV) of under
    59%, leading to misdiagnoses, mostly false positives, that add significant cost to the healthcare system while
    burdening healthcare resources and placing unnecessary stress on misdiagnosed patients or putting
    undiagnosed patients in harm’s way.”

    “Cardiologs is a game-changer for arrhythmia screening,” added Yann Fleureau, co-founder and CEO of
    Cardiologs Technologies. “A cardiologist recovers a digital ECG from any compatible cardiac monitoring device—
    such as a Holter monitor, smartwatch, ECG patch or even a connected t-shirt—then uploads it to the Cardiologs
    cloud and is able to immediately leverage our technology to identify relevant events. It is especially powerful for
    long-term recordings that used to require a very laborious manual analysis process.
    “Our Cardiologs team has trained a neural network using more than 500,000 recordings, and this training dataset
    keeps growing,” said Fleureau. “The result is that Cardiologs is designed to recognize patterns in a cardiac signal
    for fast and precise analysis of arrhythmias such as AFib in a similar intuitive manner as expert cardiologists.
    We especially bring the P-wave detection (atrial activity) to a whole new level, which explains our radically better
    PPV,” said Fleureau.

    Scientific Validation of Cardiologs. When defining the reliability of diagnosing AFib and other arrhythmias, the
    term Positive Predictive Value (PPV) refers to the percentage of true positive cases among total cases detected.
    Conventional “state-of-the-art” PPV for detecting AFib is less than 59%1

    . The PPV for Cardiologs’ detection of
    AFib was 91%2 included in the cleared FDA submission. In addition, also as included in the cleared FDA
    submission, Cardiologs’ sensitivity for detecting AFib was reported to be 97%3 (the percentage of positive cases
    truly identified) and was superior to “state-of-the-art” conventional methods of detecting AFib and other
    arrhythmias. Cardiologs’ study results have been published in the European Journal of Preventive Cardiology
    (2016, Vol. 23(2S 41-55). The study’s investigators concluded: “This (Cardiologs) method may be more reliable
    and accurate than previous methods in the diagnosis of AFib on long-duration ambulatory ECG and other
    monitoring devices.”

     

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