• Can tattoos embrace technology in order to make the skin interactive?

    The DermalAbyss project is the result of a collaboration between MIT researchers Katia Vega, Xin Liu, Viirj Kan and Nick Barry and Harvard Medical School researchers Ali Yetisen and Nan Jiang.

    DermalAbyss is a proof-of-concept that presents a novel approach to bio-interfaces in which the body surface is rendered an interactive display. Traditional tattoo inks are replaced with biosensors whose colors change in response to variations in the interstitial fluid. It blends advances in biotechnology with traditional methods in tattoo artistry.

    This is a research project, and there are currently no plans to develop Dermal Abyss as a product or to pursue clinical trials.

     

    Creative Common Attribution-NonCommercial 4.0 International

    We investigated four biosensors, reacting to three pieces of biochemical information in body fluid and changes colors: The pH sensor changes between purple and pink, the glucose sensor shifts between blue and brown; the sodium and a second pH sensor fluoresce at a higher intensity under UV light.

    The Dermal Abyss creates a direct access to the compartments in the body and reflects inner metabolic processes in a shape of a tattoo. It could be used for applications in continuously monitoring such as medical diagnostics, quantified self, and data encoding in the body.

    Currently, during daily activities and alimentary habits, diabetics need to monitor their glucose levels by piercing the skin, 3 to 10 times per day. With Dermal Abyss, we imagine the future where the painful procedure is replaced with a tattoo, of which the color from pink to purple based on the glucose levels. Thus, the user could monitor the color changes and the need of insulin.

    Preliminary evaluation was done in an ex vivo pig skin model. Several injections in the skin were done in order to understand the visibility and functionality of the biosensors.

    Publication: Katia Vega, Nan Jiang, Xin LIU, Viirj Kan, Nicolas Barry, Ali Yetisen, Pattie Maes and Joe Paradiso. “The Dermal Abyss: Interfacing with the Skin by Tattooing Biosensors” In Proceedings of the 2017 ACM International Symposium on Wearable Computers. ACM, 2017.  (to appear)

    PH sensing: low value

    PH  sensing: high value

    Current biosensors still have limitations that future researchers should address before implantation.

    1. The range of colors and intensities of the current biosensors should be extended to enable higher-resolution information. The optimization of the detection range and the selectivity of the existing biosensors will accelerate their translation to the clinic or market.
    2. The safety profile of these biosensors must also be characterized, beginning first with cytoxicity assays and biocompatibility in vitro before progressing to in vivo animal studies to determine systemic biocompatibility, in terms of toxicity and interference with normal tissue function.
    3. Long-term in vivo researches will be needed for establishing the retention of the biosensors in the skin and to quantify biosensor diffusion in tissue. One potential research direction would be to conjugate the biosensors to polymeric microspheres through acrylate groups to prevent diffusion into tissues.

    Credits

    Katia Vega, Viirj Kan, Xin Liu, Nick Barry, Pattie Maes, Joseph Paradiso
    MIT Media Lab, Cambridge, Massachusetts, United States

    Nan Jiang, Ali Yetisen, Ali Khademhosseini, Seok-Hyun Yun
    Harvard Medical School, Cambridge, Massachusetts, United States

     

    Comments are closed

    Sorry, but you cannot leave a comment for this post.

     

    Latest Posts

    Latest Video

     
     

    LATEST POSTS

    What To Expect When Going To A Local Therapist

    Much of the population still looks down on therapy and psychologists. The primary reason for this is that therapy is vastly misunderstood by the general…

    Calm Body and Calm Mind: 4 Stress-Relief Strategies You Can Try

    Stress comes in different ways. First, stress can be in the form of acute stress. Acute stress is the kind of stress that you acquire,…

    Programming the Subconscious to Fight Diabetes

    Diabetes is a life-threatening illness that causes strokes, heart attacks, kidney failure, and blindness. Every year, 1.5 million Americans learn they have the illness. For…

    Vision of the Future in AR and Mixed Reality

    SOURCE Hello everyone who is reading our blog In this post I would like to share some of my thoughts and observations on how different…

    Keeping out of Trouble: 3 Scenarios Where Health Insurance Can Drop You

    Your health insurance is incredibly important, which is why the idea of being dropped by your insurance company is so concerning. Your health insurance provider…

    Health Benefits Associated With Drinking Water

      Out all the things that we eat and drink, water stands out as the most important one. When you drink water the body is…

    Artificial Intelligence Diagnoses Heart Murmurs Better Than Expert Cardiologists

    SOURCE Eko’s heart murmur detection algorithm outperformed four out of five cardiologists for the detection of heart murmurs in a recent clinical study. The algorithm…

    https://ford.niko.ua

    Узнайте про интересный web-сайт на тематику штори тюль.